Quality Control

PHARMACEUTICAL LABORATORY

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Pharmaceutical Laboratory:

Keeping drugs cool on the bench

pharmaceutical laboratory

A private biopharmaceutical company formulates drugs that are sensitive to temperature. TECA Model AHP-1200 CPV is their perfect benchtop cooling solution. The customer uses the AHP-1200 CPV Cold Plate in combination with the customer’s own aluminum blocks to keep solutions at 0C during filtration and vial filling operations.

The customer reports, “We have been very satisfied”. This customer provided photo is a wonderful example of the versatility of TECA’s line of Laboratory Cold/Hot Plates. The plate surfaces are appropriately sized to accept microtiter plates and other lab accessories. The temperature can be read from either the plate surface or anywhere a remote sensor can be placed, via the Remote Sensibility™ feature.

LABORATORY APPLICATION

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Laboratory Application:

laboratory application laboratory application

 

In March our customer said: “We are most likely going to soon order 1 of the AHP-301CPV.”

First though, can you please provide a quote on the manufacture of a top plate? We would like to fit:

  • 2 x 500 mL Schott bottles (the one I measured was 86mm diameter)
  • 2 x 250 mL Schott bottles (the one I measured was 68mm diameter)
  • 2 x 50 mL Schott bottles (the one I measured was 46mm diameter)

I’d guess that Schott do not make their bottles to too tight specifications, so we would need to allow some room for tolerances. What do you think? These could be arranged in any way that fit best and that minimized any top plate overhang over the cold plate beneath. We can foresee out-growing the 50 mL bottles, so ideally would like the ‘walls’ surrounding the 50 mL wells to be thick enough to later be drilled out so that the wells can accommodate 100 mL Schott bottles (the one I measured was 56mm diameter). The height of the top plate (i.e. depth of the wells) only need be about 70 mm. For the current application, we only need to chill to about 5 deg °C. Does the range we are interested in affect anything?

In May we shipped the custom “Beaker Block: and AHP-301CPV.

ELECTRONIC TEST STATION

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Electronic Test Station:

electronic test station

An aerospace contractor was interested in a large cold plate for the testing of electronic components.  We first offered them the AHP-1200CPV but they responded that the AHP-1200DCP was more the size they wanted.  Could we change it to a single plate?  Well, we couldn’t change the plate size but we could add an accessory plate which was larger.  And we could build the unit with one controller including all of the standard options.

Now they are using the 12” x 18” custom accessory plate and a special AHP-1200DCP to test electronic amplifiers by ramping the temperature up and down between +10 °C to +70 °C.  A custom solution at very nearly standard product price to fill a not so unusual need.

EQUIPMENT TESTING AND MAINTENANCE

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Equipment Testing & Maintenance:

equipment testing

Three AHP-1200CPV Cold Plates are running continuously and in tandem at 17 °C to monitor satellite equipment. The customer has added air deflectors of his own design. TECA offers standard air deflectors as well. The customer applies approximately 50 Watts of heat to the cold plate.

QUALITY CONTROL

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Quality Control:

quality control quality control

 

The AHP-1200CPV is used in a customer’s Quality Control inspection process. The customer required a specific piece of equipment that would allow for bench top inspection of solution samples contained in small vials. Maintaining a 5C temperature throughout the QC inspection process was crucial.

Ease of use and dependable control by TECA Model AHP-1200CPV Cold Plate has made the customer’s process more efficient.

CONSUMER ELECTRONICS

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Consumer electronics:

consumer electronics

They manufacture navigation devices for land, road, trail and water and they needed to evaluate circuit boards @ various temperatures (-30 °C to -40 °C, no or minimal heat load, room temperature ambient) and on recommendation of a person who joined them from a controls company and had been using the solid state cold plate AHP-1200CAS. The system required the cold plate, cascade, cascade control and tapped plate. The tapped plate is built into the cold plate in place of a smooth plate surface to attach to the cascade plate.

The cascade control facilitates power and temperature control to the cascade. The system also included an acrylic cover and insulation block. They received the system and liked how it is built.

CASCADE COLD PLATE

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Cascade Cold Plate:

cascade cold plate cascade cold plate

 

Here’s a step by step of an AHP-1200CAS/CCP-22 Cascade system our engineers were playing with. They took a purple EasySep magnetic nano particle vessel, set it on the cascade, insulated it and then cycled it up and down for kicks. The curve shows the results. Faster times can be achieved by thinning out the plates and building the cascade into the AHP-1200CAS rather than having it as an option.

Talk to TECA engineers if your interested.

TITER PLATE COOLING

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Titer Plate Cooling:

titer plate cooling AHP-300CP

The WWW brings many to TECA’s door. These particular customer requirements were filled by an AHP-300CP Peltier cold plate. He needed to control the temperature of a 96 well titer plate in a new product design. But he needed just a few things the standard unit didn’t provide and he didn’t need some that it did provide. He wanted a 24 VDC heat cool system with continuous fan operation and a custom tap pattern on the cold plate.

In short order the TECA sales team assigned a preliminary part number, passed the requirements through to engineering and together the first units were modified and shipped. This gave the customer plenty of time to work with the solid state cold plates and refine his requirements into the custom design he uses today.

The AHP-300CP series is now replaced by a newer and more efficient model the AHP-470CP series.

INDUSTRIAL ADHESIVE COOLING

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Industrial Adhesive Cooling:

industrial adhesive cooling

These folks needed to cool a thick fluid that ends up being gaskets when robotically dispensed. A custom version of our AHP-1200CP fit the bill perfectly. Now the product is dispensed consistently because of the temperature control provided by thermoelectrics.

BEVERAGE COOLING IN A BARREL

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Beverage Cooling in a barrel:

beverage cooling in a barrel beverage cooling in a barrel

Here’s an application that TECA’s engineering team was particularly excited about. Not because of the economics or the potential new business. Frankly we didn’t think the market was there. But as soon as they found out that a ½ barrel of beer would be needed for testing they were all over it. While none was ever sold, good lessons regarding contact methods and material stratification were learned. To see the result of the test click here.
We used an AHP-1200CP thermoelectric cold plate and a TLC-700 thermoelectric liquid chiller for testing purpose.

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